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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
48.79
Human Site:
T1268
Identified Species:
67.08
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
T1268
R
L
I
G
I
Y
K
T
Y
N
I
T
K
S
V
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
T1268
R
L
I
G
I
Y
K
T
Y
N
I
T
K
S
V
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
T1267
R
L
I
G
I
Y
K
T
Y
N
I
T
K
S
V
Dog
Lupus familis
XP_535848
1288
147094
T1268
R
L
I
G
I
Y
K
T
Y
N
I
T
K
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
T1266
R
L
I
G
I
Y
K
T
Y
N
S
T
K
S
V
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
P1205
E
S
L
I
G
V
Y
P
E
Q
G
D
C
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
T1050
N
T
T
K
S
V
A
T
N
P
K
L
I
A
S
Chicken
Gallus gallus
NP_989849
1274
145838
T1239
R
L
I
G
I
Y
K
T
H
N
T
T
K
S
V
Frog
Xenopus laevis
P50532
1290
146971
T1262
R
L
I
G
I
Y
K
T
H
N
T
T
K
S
V
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
T1267
R
L
I
G
I
Y
K
T
H
N
P
T
K
N
V
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
T1263
R
L
I
G
I
Y
K
T
H
N
T
T
K
S
V
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
S1643
E
D
C
P
I
Q
G
S
E
D
Q
D
Y
S
T
Honey Bee
Apis mellifera
XP_396862
1282
148175
T1181
Y
L
V
G
I
Y
K
T
Y
N
C
T
K
S
V
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
V1355
R
L
V
G
I
Y
K
V
D
G
C
T
R
N
V
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
T1265
R
L
V
G
I
Y
K
T
H
N
C
S
K
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
T1219
R
L
V
G
I
Y
K
T
D
N
C
T
K
S
I
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
N1375
Y
I
K
E
R
T
K
N
A
Q
F
I
V
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
6.6
86.6
86.6
80
86.6
13.3
80
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
13.3
93.3
93.3
93.3
93.3
26.6
86.6
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
6
0
6
0
0
0
0
6
0
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
24
0
6
0
0
% C
% Asp:
0
6
0
0
0
0
0
0
12
6
0
12
0
0
0
% D
% Glu:
12
0
0
6
0
0
0
0
12
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
77
6
0
6
0
0
6
6
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% H
% Ile:
0
6
53
6
83
0
0
0
0
0
24
6
6
6
12
% I
% Lys:
0
0
6
6
0
0
83
0
0
0
6
0
71
0
0
% K
% Leu:
0
77
6
0
0
0
0
0
0
0
0
6
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
0
6
6
71
0
0
0
12
0
% N
% Pro:
0
0
0
6
0
0
0
6
0
6
6
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
12
6
0
0
0
0
% Q
% Arg:
71
0
0
0
6
0
0
0
0
0
0
0
6
0
0
% R
% Ser:
0
6
0
0
6
0
0
6
0
0
6
6
0
65
12
% S
% Thr:
0
6
6
0
0
6
0
77
0
0
18
71
0
6
6
% T
% Val:
0
0
24
0
0
12
0
6
0
0
0
0
6
6
71
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
77
6
0
36
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _